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| Antigenic Specificity | Alkaline Phosphatase, Liver/bone/kidney (ALPL) (aa 18-32), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. Liver/bone/kidney alkaline phosphatase, also known as tissue-nonspecific alkaline phosphatase, acts physiologically as a lipid-anchored phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP) ectophosphatase Mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of rat Alkaline Phosphatase(18-32aa, FVPEKEKDPSYWRQQ), different from the related mouse sequence by one amino acid. |
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| Other Names | ALP|iap|alpl|AP-TNAP|APTNAP|HOPS|TNAP|TNSALP|Akp-2|Akp2|PHOA|TNS-AP |
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| Gene, Accession # | Gene ID: 25586 |
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| Catalog # | ABIN1672906 |
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| Price | |
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| Order / More Info | Alkaline Phosphatase, Liver/bone/kidney (ALPL) (aa 18-32), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 3532105, 3446011 |
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