| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Pdk1) |
|---|
| Description | Purity > 85% as determined by SDS-PAGE. MW: 48.7kDa. Full Length of Mature Protein: 27-434aa. N-terminal 10xHis-tagged. Mus musculus (Mouse). Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Pyruvate dehydrogenase kinase isoform 1 |
|---|
| Gene, Accession, CAS # | Pdk1, UniProt: Q8BFP9 |
|---|
| Catalog # | RPC20694 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Pdk1) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|