| 产品详情 |
| Edit |   |
| Antigenic Specificity | NCF4 |
| Clone | OTI4B5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100 µl |
| Concentration | n/a |
| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NCF4 Monoclonal Antibody (OTI4B5). Nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase is a multimeric enzyme system that mediates electron transport from NADPH in the cytoplasm to molecular oxygen in the phagosome, thereby generating reactive oxidant intermediates. Upon neutrophil stimulation, NADPH-oxidase and other cytosolic elements localize to the cell membrane from the cytosol to form a complex which produces phagocytic oxygen radicals. There are a number of cytosolic proteins that are involved in NADPH-oxidase activation/ deactivation, including p47-phox, p67-phox, p40-phox and the small GTP-binding protein, Rac. Activation of NADPH oxidase is accompanied by the phosphorylation of cytosolic components p40-phox, p47-phox and p |
| Immunogen | n/a |
| Other Names | NCF4; P40PHOX; neutrophil cytosolic factor 4, 40kDa ; CTA-833B7.1; MGC3810; NCF; SH3PXD4; OTTHUMP00000028736; OTTHUMP00000043756; neutrophil NADPH oxidase factor 4; neutrophil cytosol factor 4; neutrophil cytosolic factor 4 (40kD) |
| Gene, Accession # | Entrez: 4689; Uniprot: Q15080 |
| Catalog # | MA5-27094 |
| Price | |
| Order / More Info | NCF4 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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