| 产品详情 |
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| Product Name | Human Inosine-5?-Monophosphate Dehydrogenase II, human recombinant |
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| Description | Inosine monophosphate dehydrogenase, IMPDH, (E.C. 1.1.1.205) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis and it is essential for lymphocyte proliferation. IMPDH oxidizes inosine 5'-monophosphate (IMP) to xanthine 5'-monophosphate (XMP) using NAD as a cofactor. It plays a critical role in cell growth and in the malignancy of some tumors. IMPDH II is the predominant isoform of IMPDH and is specifically linked to a wide range of cancers and lymphocyte proliferation. BioVision's active human IMPDH II is suitable for functional assays, high-throughput screening and preclinical studies in drug discovery. MW: 57 kDa. Purity > 90% |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | IMP dehydrogenase type II, IMPDH II, IMPD2, IMPDH |
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| Gene, Accession, CAS # | IMPDH2, Gene ID: 3615, Accession: P12268 |
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| Catalog # | P1131-20 |
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| Order / More Info | Human Inosine-5?-Monophosphate Dehydrogenase II, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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