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| Antigenic Specificity | RASGRP3 |
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| Clone | OTI2G7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RASGRP3 Monoclonal Antibody (OTI2G7). Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]). |
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| Immunogen | n/a |
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| Other Names | OTTHUMP00000201245; calcium and DAG-regulated guanine nucleotide exchange factor III; guanine nucleotide exchange factor for Rap1; ras guanyl-releasing protein 3 |
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| Gene, Accession # | Entrez: 25780; Uniprot: Q8IV61 |
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| Catalog # | MA5-26500 |
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| Price | |
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| Order / More Info | RASGRP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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