| 产品详情 |
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| Product Name | Interleukin 33 (IL33) (AA 109-266) (Active) protein |
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| Description | Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | IL33|C9orf26|DVS27|IL1F11|NF-HEV|NFEHEV|RP11-575C20.2|9230117N10Rik|Il-33|Il1f11|RGD1311155 |
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| Gene, Accession, CAS # | Gene ID: 90865, 77125 |
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| Catalog # | ABIN1343980 |
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| Order / More Info | Interleukin 33 (IL33) (AA 109-266) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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