| 产品详情 |
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| Antigenic Specificity | PCNA |
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| Clone | 1C11 |
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| Host Species | Mouse |
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| Reactive Species | human, rat, rabbit |
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| Isotype | IgG |
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| Format | Protein G purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PCNA(1C11) Monoclonal Antibody. • Target Background: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the repl |
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| Immunogen | KLH conjugated synthetic peptide derived from human PCNA. Immunogen Range: 200-250/261 |
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| Other Names | ATLD2; Proliferating cell nuclear antigen; PCNA; Cyclin |
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| Gene, Accession # | Gene ID: 5111, SwissProt: P12004 |
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| Catalog # | bsm-2006M |
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| Price | |
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| Order / More Info | PCNA Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Chen, X. et al. (2013) Int J Clin Exp Pathol 6.11: 2280-2291. PubMed: 24228089 // Jiang, Tao, et al. (2015) Int J Clin Exp Pathol. 8.11: 13945. PubMed: 26823706 // Zhang, Zhongwei, et al.(2016) Microb Biotechnol. PubMed: 27641625 // Zhang et al. (2015) World.J.Gastroenterol. 21:4195-209. PubMed: 25892869 |
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