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| Product Name | Glycogen Synthase Kinase 3 alpha, Fusion Protein, Recombinant (GSK3a) |
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| Description | Purified by affinity chromatography. GSK-3 is one of the Akt substrates. It can be phosphorylated by Akt at Ser21 of GSK-3a or Ser9 of GSK-3b. The phosphorylation of GSK negatively regulates its kinase activity. The recombinant GSK-3a fusion protein serves as a useful substrate for assaying Akt kinase activity. Product Description: E. coli-expressed recombinant fusion protein of GSK-3alpha residues (amino acids 12-30, UniProt accession #P49840) surrounding GSK-3a Ser21 and Glutathione S-transferase (GST). Activity: GSK-3a fusion protein at a concentration of 2ug/20ul reaction was phosphorylated in an in vitro kinase assay with 200 mM ATP. After 30 minutes incubation at 30°C, phosphorylation was detected by Western blot with phospho-speci?c GSK-3a antibodies. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P49840 |
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| Catalog # | G8170-42A |
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| Order / More Info | Glycogen Synthase Kinase 3 alpha, Fusion Protein, Recombinant (GSK3a) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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