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Product Name | Glutathione S-Transferase pi, Western Blot Positive Control (GSTpi) |
Description | Control peptide for G8135-26H. GST's are responsible for the metabolism of a broad range of xenobiotics and carcinogens. The enzyme catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a reaction that is sometimes a first step in a detoxification process leading to mercapturic acid formation. Based on aa sequence similarities and antibody cross-reactivities, the mammalian cytosolic GSTs are divided into the following classes: alpha, mu, kappa, theta, pi, zeta, omega and sigma. GSTs exists as homodimers of ~25kD. GST A1-1 is mainly found in kidney, intestine, lung, and liver. GST M1-1 is restricted to liver and few other tissues. GST P1-1 has a widespread distribution in most tumor cells and tissues but it is absent in liver. The GST M1-1 is the type b allelic variant and corresponds to human GST Y. GST Pi/ GST P1/ GST3, a 210aa protein (chrm 11q13) is present in all tissues and cells, with the exception of red cells, in which only erythrocy |
Size | 100ul |
Concentration | n/a |
Applications | WB |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | G8135-26D |
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Order / More Info | Glutathione S-Transferase pi, Western Blot Positive Control (GSTpi) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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