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Product Name | KRT8, Recombinant, Human, aa1-483, His-Tag |
Description | Purity ~90% (SDS-PAGE). KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Source: Recombinant protein corresponding to human KRT8, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~56kD (506aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSIRVTQ KSYKVSTSGP RAFSSRSYTS GPGSRISSSS FSRVGSSNFR GGLGGGYGGA SGMGGITAVT VNQSLLSPLV LEVDPNIQAV RTQEKEQIKT LNNKFASFID KVRFLEQQNK MLETKWSLLQ QQKTARSNMD NMFESYINNL RRQLETLGQE KLKLEAELGN MQGLVEDFKN KYEDEINKRT EMENEFVLIK KDVDEAYMNK VELESRLEGL TDEINFLRQL YEEEIRELQS QISDTSVVLS MD |
Size | 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | KRT8, Recombinant, Human, aa1-483, His-Tag (Keratin Type II Cytoskeletal 8, Keratin 8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO) |
Gene, Accession, CAS # | n/a |
Catalog # | 137103 |
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Order / More Info | KRT8, Recombinant, Human, aa1-483, His-Tag from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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