| 产品详情 |
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| Product Name | Recombinant Zaire ebolavirus Membrane-associated protein VP24 (VP24) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 35.7kDa. Full Length: 1-251aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Zaire ebolavirus (strain Gabon-94) (ZEBOV) (Zaire Ebola virus). Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta and IFN-gamma signaling pathways. Blocks the IFN-induced nuclear accumulation of host phosphorylated STAT1, by interacting with the STAT1-binding region of host importin alpha-1/KPNA1 protein, thereby inhibiting the latter. Without the activity of this protein, activated STAT1 would not enter the nucleus and be unable to activate IFN-induced genes. Plays a role in assembly of viral nucleocapsid and virion budding. May act as a minor matrix protein that plays a role in assembly of viral nucleocapsid and virion budding. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | VP24, UniProt: O11459 |
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| Catalog # | RPC26282 |
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| Order / More Info | Recombinant Zaire ebolavirus Membrane-associated protein VP24 (VP24) from BIOMATIK |
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| Product Specific References | n/a |
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