| 产品详情 |
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| Product Name | AZD8055 |
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| Description | A potent, ATP-competitive inhibitor of mTOR kinase (both mTORC1 and mTORC2) with an IC50 of 0.8 nM. AZD8055 displays excellent selectivity (~ 1,000-fold) against all class I PI3K isoforms and other members of the PI3K-like kinase family. In addition, it shows no significant activity against a panel of 260 kinases at concentrations up to 10 µM. AZD8055 inhibits the phosphorylation of mTORC1 substrates p70S6K and 4E-BP1 as well as phosphorylation of the mTORC2 substrate AKT and downstream proteins. MW: 465.54. Purity ≥98% by HPLC |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol |
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| Gene, Accession, CAS # | CAS: 1009298-09-2 |
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| Catalog # | 2340-1 |
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| Order / More Info | AZD8055 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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