| 产品详情 |
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| Product Name | CD40 Ligand (CD40LG) (AA 116-261), (AA 18-111) protein (DYKDDDDK Tag) |
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| Description | CD40L is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo. It provides a simple and equally potent alternative to combinations. CD40L has shown to suppress alum-induced IL-1beta release and caspase-1 activation in a dose-, CD40- and time dependent manner, without affecting BMDM viability. It also effectively suppressed the inflammasome function triggered by NLRP3 activators. The secretion of caspase-1 independent inflammatory mediators has been shown to be unaltered or even enhanced. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD154|cd40l|CD40L|HIGM1|IGM|IMD3|T-BAM|TNFSF5|TRAP|gp39|hCD40L|CD40-L|Cd40l|Ly-62|Ly62|Tnfsf5 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN1344289 |
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| Price | |
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| Order / More Info | CD40 Ligand (CD40LG) (AA 116-261), (AA 18-111) protein (DYKDDDDK Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 12556501, 15315967, 25780036 |
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