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Product Name | Lck Inhibitor |
Description | Purity >95%. Lymphocyte-speci?c protein tyrosine kinase (Lck) is a member of the Src-family of non-receptor protein tyrosine kinases and plays a critical role in the initial steps of T cell receptor signaling that trigger the production of cytokines. Lck inhibitor is a pyrrolopyrimidine that blocks the activity of two forms of Lck kinase, Lck (64-509) and Lckcd, with IC50 values of 33, >50, and >50 µM, respectively). This compound has been shown to inhibit T cell receptor-stimulated IL-2 production in mice (ED50 s = 4 and 25 mg/kg when administered either i.p. or orally). |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Lymphocyte-specific protein tyrosine kinase, RK-24466 |
Gene, Accession, CAS # | CAS: 213743-31-8 |
Catalog # | LS-H8427 |
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Order / More Info | Lck Inhibitor from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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