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| Product Name | CHM, Recombinant, Human, aa1-653, His-Tag (Rab Proteins geranylgeranyltransferase Component A 1) |
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| Description | Purity ~90% (SDS-PAGE). Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation. Source: Recombinant protein corresponding to aa1-653 from human CHM, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~77.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Choroideremia protein, Rab escort protein 1, REP-1, TCD protein |
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| Gene, Accession, CAS # | SwissProt: P24386 |
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| Catalog # | 372751 |
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| Order / More Info | CHM, Recombinant, Human, aa1-653, His-Tag (Rab Proteins geranylgeranyltransferase Component A 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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