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Product Name | CCL7/MCP-3 BioAssay™ ELISA Kit, Human |
Description | Sandwich ELISA quantitative detection kit for Human CCL7/MCP-3 in cell culture supernates. serum and plasma (heparin, EDTA). Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, mapped the MCP3 gene to chromosome 17q11.2-q12.1 MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, suggested that matrix metalloproteinases are both effectors and regulators of the inflammatory response.2 Assay Range: 15.6pg/ml-1000pg/ml Sensitivity: < 1 pg/ml Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Uniprot ID: P80098 Entrez Gene ID: 6354 Kit Components: 96-well plate pre-coated with anti- |
Size | 96 tests |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | Gene ID: 6354, SwissProt: P80098 |
Catalog # | 143755 |
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Order / More Info | CCL7/MCP-3 BioAssay™ ELISA Kit, Human from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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