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Product Name | Epiregulin (EREG), human recombinant |
Description | Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and Vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant human EREG |
Size | 1 mg |
Concentration | n/a |
Applications | RUO |
Other Names | Epiregulin, EREG |
Gene, Accession, CAS # | EREG, Gene ID: 2069, Accession: O14944 |
Catalog # | 4069-1000 |
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Order / More Info | Epiregulin (EREG), human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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