| 产品详情 |
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| Product Name | AZD-6482 |
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| Description | MW: 408.45. Purity ≥98% by HPLC. AZD-6482 is a potent and selective inhibitor of PI 3-kinase beta (PI 3-Kbeta) (IC50 values are 0.69; 13.6; 47.8 and 136 nM for PI 3-Kbeta; PI 3-Kdelta; PI 3-Kgamma and PI 3-Kalpha; respectively). It displays 80-fold selectivity for PI3Kbeta over PI3k-C2 and DNA-PK and more than 1; 000-fold over other PI3K-related kinases. AZD6482 blocks Akt signaling and tumor growth in a large number of cancer cell lines; including those that are dependent on PI3Kbeta activat |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [(-)-2-[[ (1R)-1-[7-Methyl-2- (4-morpholinyl)-4-oxo-4H-pyrido[1; 2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid] |
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| Gene, Accession, CAS # | CAS: 1173900-33-8 |
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| Catalog # | MBS846286 |
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| Price | |
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| Order / More Info | AZD-6482 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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