| 产品详情 |
| Edit |   |
|---|
| Product Name | AZD-6738 |
|---|
| Description | MW: 412.51. Purity ≥98% by HPLC. AZD6738 is a potent ATR kinase inhibitor with IC50 value of 1 nM against the isolated enzyme. AZD6738 selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling; and results in the inhibition of DNA damage checkpoint activation; disruption of DNA damage repair; and the induction of tumor cell apoptosis. It also induces cell death and senescence in non-small cell |
|---|
| Size | 5 mg, 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [4-[4-[1-[[S (R) ]-S-methylsulfonimidoyl]cyclopropyl]-6-[ (3R)-3-methyl-4-morpholinyl]-2-pyrimidinyl]-1H-pyrrolo[2; 3-b]pyridine] |
|---|
| Gene, Accession, CAS # | CAS: 1352226-88-0 |
|---|
| Catalog # | MBS846310 |
|---|
| Price | |
|---|
| Order / More Info | AZD-6738 from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|