产品详情 |
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Product Name | Azidothymidine |
Description | Azidothymidine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 µM). Displays 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency. MW: 267.24. Purity ≥98% by HPLC |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3'-Azido-3'-deoxythymidine; AZT; Zidovudine |
Gene, Accession, CAS # | CAS: 30516-87-1 |
Catalog # | B1113-50 |
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Order / More Info | Azidothymidine from BIOVISION, INC. |
Product Specific References | n/a |
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