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| Product Name | SCH 529074 |
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| Description | Restores mutant p53 activity. Binds p53 DNA binding domain (Kd = 1-2 μM) and restores wild-type function to many oncogenic mutants by acting as a chaperone. Inhibits ubiquitination of p53 by HDM2. Triggers apoptosis in tumor cell lines and reduces tumor growth in a xenograft model. Purity 98%. MW (observed): 563.56 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N3-[2-[[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]methyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine |
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| Gene, Accession, CAS # | CAS: 922150-11-6 |
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| Catalog # | 4240/10 |
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| Price | |
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| Order / More Info | SCH 529074 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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