| 产品详情 |
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| Product Name | Naquotinib |
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| Description | An irreversible inhibitor of mutant EGFRs; inhibits cell proliferation of Ba/F3 cells expressing various EGFR mutations (IC50s= 9-11 nM); selective for mutant EGFRs over wild-type EGFR (IC50 = 830 nM); reduces phosphorylated levels of EGFR, AKT, and ERK and decreases cell viability in NSCLC cells and cells carrying an exon 20 insertion mutation; reduces tumor growth in PC-9/NaqRc2 mouse xenograft model at 50 mg/kg per day |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | F-3 T-790-M L-858-R C-797-S PC9 NaqRc-2 ASP8273 ASP-8273 |
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| Gene, Accession, CAS # | CAS: 1448232-80-1 |
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| Catalog # | 23498-1 |
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| Price | |
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| Order / More Info | Naquotinib from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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