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| Product Name | Galectin-1, Recombinant, Human |
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| Description | Chromatographically purified ~95% by SDS-PAGE, RP-HPLC. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 is an autocrine negative growth factor that regulates cell proliferation. Galectin-1 regulates cell apoptosis and cell differentiation. Galectin-1 binds CD45, CD3 and CD4 & inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of lyn kinase. Galectin-1 and its ligands are one of the master regulators of immune responses as T-cell homeostasis and survival, T-cell immune disorders, inflammation and allergies as well as host-pathogen interactions. Galectin-1 expression or overexpression in tumors and/or the tissue surrounding them must be considered as a sign of the malignant tumor progression that is often related to the long-range dissemination of tumoral cells (metastasis), to their dissemination into the surrounding normal tissue, and to tumor immune-escape. Galectin- |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Galectin-1, Recombinant, Human (GAL1, LGALS1, GAL-1, Lectin galactoside-binding soluble 1, Beta-galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14kD lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZp686E23103) |
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| Gene, Accession, CAS # | Accession: NP_005558.1 |
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| Catalog # | G1044-47B |
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| Order / More Info | Galectin-1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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