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Product Name | Galectin-3, Recombinant, Human (IgE-binding protein, MAC2, L-29, CPB-35) |
Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells.The Galectins are lectins that recognize and interact with beta-galactoside moieties.Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis.Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages.Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes.Expression of Galectin-3 is affected by neoplastic transformation, being up-regulated in certain types of lymphomas, and in thyroid and hepatic carcinomas.Conversely, it is down-regulate |
Size | 10ug, 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | 143337 |
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Order / More Info | Galectin-3, Recombinant, Human (IgE-binding protein, MAC2, L-29, CPB-35) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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