| 产品详情 |
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| Product Name | Recombinant Human Bifunctional polynucleotide phosphatase/kinase (PNKP) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 73.1kDa. Full Length: 1-521aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either roving 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | DNA 5'-kinase/3'-phosphatasePolynucleotide kinase-3'-phosphatase 2 domains:Polynucleotide 3'-phosphatase (EC:3.1.3.32); 2' (3')-polynucleotidasePolynucleotide 5'-hydroxyl-kinase (EC:2.7.1.78) |
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| Gene, Accession, CAS # | PNKP, UniProt: Q96T60 |
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| Catalog # | RPC23497 |
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| Price | |
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| Order / More Info | Recombinant Human Bifunctional polynucleotide phosphatase/kinase (PNKP) from BIOMATIK |
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| Product Specific References | n/a |
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