| 产品详情 |
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| Antigenic Specificity | Human IL-23 |
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| Clone | 37I30M34 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human IL-23 monoclonal antibody for WB. IL-23 is a member of the IL-12 cytokine family which is produced by dendritic cells and other antigen presenting cells in the peripheral tissues. This cytokine is a heterodimer composed of an IL-12p40 subunit, and a p19 subunit. IL-23 plays an important role in stimulating memory T-cells. It is also required for the induction, expansion, maintenance, and downstream effector functions of Th17 cells. Th17 cells play a vital role in upregulating neutrophil chemokines and various pro-inflammatory cytokines. IL-23 interacts with the receptors IL-12R beta1 and IL-23R to activate the Jak-Stat signaling cascade. |
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| Immunogen | Peptide corresponding to amino acids 55-67 of human Interlukin-23 |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 51561, UniProt: Q9NPF7 |
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| Catalog # | CABT-L1403 |
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| Price | |
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| Order / More Info | Human IL-23 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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