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Product Name | Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) (AA 42-995) protein (His tag) |
Description | Integrin alpha-5 belongs to the Integrin alpha chain family and contains 7 FG-GAP repeats. Integrin alpha-5 joins with Integrin-beta1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin alpha-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.Alternative Names: Integrin Alpha-5, CD49 Antigen-Like Family Member E, Fibronectin Receptor Subunit Alpha, Integrin Alpha-F, VLA-5, CD49e, ITGA5, FNRA |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | ITGA5|Cd49e|Fnra|VLA5|CD49e|FNRA|VLA5A|Itga5_retired |
Gene, Accession, CAS # | Gene ID: 3678 |
Catalog # | ABIN1096987 |
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Order / More Info | Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) (AA 42-995) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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