| 产品详情 |
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| Antigenic Specificity | PPP1R15A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human PPP1R15A polyclonal antibody for IHC. Protein phosphatase 1 regulatory subunit 15A, also known as, Growth arrest and DNA damage-inducible protein GADD34 or Myeloid differentiation primary response protein MyD116 homolog, and encoded by the gene name(s), PPP1R15A or GADD34, can be triggered as a direct target of activating transcription factor4 (ATF4) under ER stress. PPP1R15A plays a pivotal role in the recovery of cells from shut-down of translation induced by ER stress. It recruits the serine/threonine-protein phosphatase (PP1) to dephosphorylate the translation initiation factor eIF2alpha, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. |
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| Immunogen | Recombinant Protein |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 23645, UniProt: O75807 |
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| Catalog # | CABT-B1623 |
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| Price | |
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| Order / More Info | PPP1R15A Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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