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| Antigenic Specificity | Human ABCB11 |
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| Clone | G-7 |
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| Host Species | Mouse |
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| Reactive Species | mouse, rat, human |
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| Isotype | IgG2a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB, IP, IF, IHC-P, ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Human Anti-ABCB11 monoclonal antibody for WB, IP, IF, IHC-P, ELISA. ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, Mdr/TAP, MRP, ALD, OABP, GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A, protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II, whose regulation may be dependent on bile salt concentration. |
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| Immunogen | This antibody raised against amino acids 1-180 of BSEP of human origin. |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 839353, UniProt: Q9Y2D9 |
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| Catalog # | CABT-L1025 |
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| Price | |
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| Order / More Info | Human ABCB11 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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