| 产品详情 |
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| Antigenic Specificity | CTLA-4 |
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| Clone | 63828 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2A |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Neutralization: 2.5-10 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CTLA-4 Monoclonal Antibody (63828). CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
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| Immunogen | n/a |
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| Other Names | CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4 |
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| Gene, Accession # | Entrez: 12477; Uniprot: P09793 |
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| Catalog # | MA5-23842 |
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| Price | |
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| Order / More Info | CTLA-4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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