| 产品详情 |
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| Antigenic Specificity | CD20 (human) |
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| Clone | CAT13.6E12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | IHC, FACS |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Intermediate differentiation stage B-cell marker. Monoclonal antibody CAT13.6E12 recognizes the CD20 antigen. CD20 belongs to the MS4A family (membrane-spanning 4-domains subfamily A). Its expression is restricted to normal and neoplastic B-cells. It is expressed by pre-B-cells in the bone marrow, and expression persists during B-cell maturation but is lost upon terminal differentiation into plasma cells. CD20 is not glycosylated. CD20 is not phosphorylated in resting B-cells, but becomes heavily phosphorylated after mitogen stimulation. Three cell surface isoforms 33, 35 and 37kD, result from differential phosphorylation of a single core 33kD protein within the cytoplasmic domain. Multiple proteins are coimmunoprecipitated with CD20, suggesting that it may be a component of a multimeric surface receptor complex. Monoclonal antibodies against CD20 are used therapeutically, such as Rituximab (Mabthera) or Britumomab (Zevalin). Application: IHC (f), FACS |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | T-1371.0100 |
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| Price | |
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| Order / More Info | CD20 (human) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.
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| Product Specific References | n/a |
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