| 产品详情 |
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| Antigenic Specificity | CENPT (phospho S47) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ICC, WB, Dot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human CENPT polyclonal antibody for ICC, WB, Dot. Centromere protein T (UniProt Q96BT3; also known as CENP-T, Interphase centromere complex protein 22) is encoded by the CENPT (also known as C16orf56, ICEN22) gene (Gene ID 80152) in human. Kinetochore complex-mediated chromosome interaction with microtubules from the mitotic spindle is essential for proper chromosome segregation during mitosis. The kinetochore is a macromolecular structure composed of almost 100 different proteins assembled upon the centromere in a cell cycle-regulated manner. CENP-T and 15 other chromatin proximal proteins constitute the Constitutive Centromere Associated Network (CCAN) present at centromeres throughout the cell cycle. Some CCAN proteins (e.g. CENPT/W complex and CENP-C) mediate DNA binding, while others (e.g. CENP-N) interact directly with CENP-A-containing nucleosomes. Evidence suggests that CENP-C and the CENP-T/W complex function as core kinetochore assembly factors in vertebrate cells. |
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| Immunogen | Linear peptide corresponding to a human CENP-T sequence containing phosphorylated Ser47. |
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| Other Names | n/a |
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| Gene, Accession # | UniProt: Q96BT3 |
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| Catalog # | CABT-B1622 |
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| Price | |
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| Order / More Info | CENPT (phospho S47) Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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