| 产品详情 |
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| Antigenic Specificity | PION |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human PION polyclonal antibody for IHC. Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of;amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311), a protease with numerous substrates. PION, or;GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both;gamma-secretase and its substrate, the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF);(He et al., 2010 (PubMed 20811458)). |
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| Immunogen | Recombinant Protein |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 54103, UniProt: A4D1B5 |
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| Catalog # | CABT-BL2903 |
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| Price | |
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| Order / More Info | PION Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 产品资料 |
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