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| Product Name | CGP 57380 |
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| Description | Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC50 = 2.2 μM) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC50 = 3 μM) and inhibits LPS-induced TNFα expression in macrophages. Purity 98%. MW (observed): 244.23 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N3-(4-Fluorophenyl)-1H-pyrazolo-[3,4-d]pyrimidine-3,4-diamine |
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| Gene, Accession, CAS # | CAS: 522629-08-9 |
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| Catalog # | 2731/10 |
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| Price | |
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| Order / More Info | CGP 57380 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21068317, 22070140, 24047601, 25187540, 25561727, 27626179, 28178522 |
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