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Product Name | Recombinant Mouse Bloom syndrome protein homolog (Blm), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 24.7kDa. Partial: 684-859aa. N-terminal 10xHis-tagged and C-terminal MYC-tagged. Mus musculus (Mouse). Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE) |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | RecQ helicase homolog |
Gene, Accession, CAS # | Blm, UniProt: O88700 |
Catalog # | RPC20981 |
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Order / More Info | Recombinant Mouse Bloom syndrome protein homolog (Blm), partial from BIOMATIK |
Product Specific References | n/a |
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