| 产品详情 |
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| Antigenic Specificity | CD181 (CXCR1) |
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| Clone | 8F1/CXCR1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, κ |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE anti-human CD181 (CXCR1). CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor that belongs to the G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower than that of CXCR2. CXCR1 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α(CXCL1). |
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| Immunogen | Human CXCR1 transfected L1.2 cells |
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| Other Names | CD128a, IL-8RA, Type I IL-8 Receptor |
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| Gene, Accession # | Gene ID: 3577 |
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| Catalog # | 320608 |
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| Price | |
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| Order / More Info | CD181 (CXCR1) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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