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| Product Name | JK 184 |
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| Description | An imidazopyridine derivative that prevents Gli-dependent transcriptional activity (IC50 = 30 nM) by inhibiting alcohol dehydrogenase 7 (IC50 = 210 nM) and depolymerizing microtubules; antiproliferative in a range of cancer cell lines (GI50s = 3-21 nM) and in pancreatic cancer xenograft models (0.2 mg/mouse/day) |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | microtubules polymerizations hedgehogs signaling Gli alcohols dehydrogenases 7 Adh7 Adh-7 Adh depolymerizing agents antiproliferative anti-proliferative proliferative anti cancers anti-cancers anticancers intracellular inhibitors inhibits inhibitions JKs JK-184 JK184 imidazopyridine derivatives HH 184 downstream Gli-dependent dependents transcriptional activity prevents functions cells lines L3.6pl L3 6pl Panc 05.04 BxPC3 D283 med Daoy pancreatic xenografts models |
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| Gene, Accession, CAS # | CAS: 315703-52-7 |
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| Catalog # | 15265-5 |
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| Price | |
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| Order / More Info | JK 184 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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