| 产品详情 |
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| Antigenic Specificity | LRRFIP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 2-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LRRFIP1 Polyclonal Antibody. Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases. |
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| Immunogen | n/a |
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| Other Names | FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP, GC-binding factor 2, LRR FLII-interacting protein 1, NEDD8-conjugating enzyme, TAR RNA-interacting protein, leucine-rich repeat flightless-interacting protein 1 |
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| Gene, Accession # | Entrez: 16978, 9208; Uniprot: Q32MZ4, Q3UZ39 |
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| Catalog # | PA5-23445 |
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| Price | |
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| Order / More Info | LRRFIP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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