| 产品详情 |
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| Antigenic Specificity | LRRK2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LRRK2 Polyclonal Antibody. Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson's disease identified to date. LRRK2, a genetic mutation, was recently found linked to about 5 percent of inherited cases of Parkinson's disease. By high-resolution recombination mapping and candidate gene sequencing in 46 families, 6 disease-segregating mutations (5 missense and 1 putative splice site mutation). It may be central to the pathogenesis of several major neurodegenerative disorders associated with parkinsonism. LRRK2 belongs to the ROCO protein family and inc |
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| Immunogen | n/a |
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| Other Names | Park8, Leucine-rich repeat (LRR) kinase 2, Leucine-rich repeat kinase 2 |
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| Gene, Accession # | Entrez: 120892, 66725; Uniprot: Q5S006, Q5S007 |
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| Catalog # | PA5-13872 |
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| Price | |
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| Order / More Info | LRRK2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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