| Edit |   |
|---|
| Antigenic Specificity | SHC |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | Alexa Fluor® 488 conjugate |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | IF(IHC-P) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | SHC Polyclonal Antibody, Alexa Fluor® 488 Conjugated. • Target Background: Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-ne |
|---|
| Immunogen | KLH conjugated synthetic peptide derived from human SHC. Immunogen Range: 480-520/583 |
|---|
| Other Names | SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1; SHC1 |
|---|
| Gene, Accession # | Gene ID: 6464, SwissProt: P29353 |
|---|
| Catalog # | bs-3572R-A488 |
|---|
| Price | |
|---|
| Order / More Info | SHC Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|