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Product Name | PKAca, Active |
Description | Most of the effects of cAMP are mediated through the phosphorylation of target proteins on serine or threonine residues by the cAMP-dependent protein kinase (AMPK). The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. The mammalian catalytic subunit has been shown to consist of three PKA gene products: C-α, C-β, and C-γ. Two PKA isoforms exist, designated types I and II, which differ in their dimeric regulatory subunits, designated RI and RII, respectively. Furthermore, there are at least four different regulatory subunits: RI-α, RI-β, RII-α, and RII-β. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to fo |
Size | 5 µg |
Concentration | 5µg/50 µl |
Applications | RUO |
Other Names | PKA, cAMP-dependent protein kinase catalytic subunit alpha |
Gene, Accession, CAS # | PRKACA, Gene ID: 5566, Accession: NM_002730. |
Catalog # | 7743-5 |
Price | |
Order / More Info | PKAca, Active from BIOVISION, INC. |
Product Specific References | n/a |
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