| 产品详情 |
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| Antigenic Specificity | MRP2 |
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| Clone | M2II-12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:20, Immunohistochemistry (Frozen): 1:20, Western Blot: 1:20-1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MRP2 Monoclonal Antibody (M2II-12). ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinem |
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| Immunogen | n/a |
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| Other Names | MRP2 |
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| Gene, Accession # | Entrez: 1244; Uniprot: Q92887 |
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| Catalog # | MA1-35677 |
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| Price | |
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| Order / More Info | MRP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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