| 产品详情 |
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| Antigenic Specificity | MRP2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MRP2 Polyclonal Antibody. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Jo |
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| Immunogen | n/a |
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| Other Names | ABCC2, CMOAT, CMOAT1, CMRP, MRP2, Canalicular multispecific organic anion transporter 1 |
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| Gene, Accession # | Entrez: 1244, 12780; Uniprot: Q8VI47, Q92887 |
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| Catalog # | PA5-49997 |
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| Price | |
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| Order / More Info | MRP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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