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| Antigenic Specificity | PC1/3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PC1/3 Polyclonal Antibody. PCSK1 (Proprotein Convertase, Subtilisin/Kexin-Type, 1), also known as PC1 or NEC1, is an enzyme that in humans is encoded by the PCSK1 gene. Proprotein convertase-1 is a neuroendocrine convertase that belongs to a family of subtilisin-like serine endoproteases that process large precursor proteins into mature bioactive products. By in situ hybridization, Seidah et al. (1991) mapped the NEC1 gene to human chromosome 5q15-q21 and mouse chromosome 13. Ohagi et al. (1996) noted that PC1 initiates the sequential processing of proinsulin to insulin by cleaving the proinsulin molecule on the C-terminal side of the dibasic peptide, arg31-arg32, joining the B-chain and C-peptide. By observing the phenotypic features in pa |
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| Immunogen | n/a |
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| Other Names | Neuroendocrine convertase 1, NEC 1, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1 |
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| Gene, Accession # | Entrez: 18548, 25204, 5122; Uniprot: P28840, P29120, P63239 |
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| Catalog # | PA5-79787 |
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| Price | |
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| Order / More Info | PC1/3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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