| Edit |   |
|---|
| Antigenic Specificity | PC4 |
|---|
| Clone | OTI4C10 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:500-1:2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PC4 Monoclonal Antibody (OTI4C10). PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity. |
|---|
| Immunogen | n/a |
|---|
| Other Names | SUB1 homolog (S. cerevisiae), P15, PC4, p14 |
|---|
| Gene, Accession # | Entrez: 10923; Uniprot: P53999 |
|---|
| Catalog # | MA5-27146 |
|---|
| Price | |
|---|
| Order / More Info | PC4 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|