| 产品详情 |
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| Product Name | AMG 21629 |
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| Description | Potent and selective TRPV1 antagonist. Blocks Ca2+ uptake by CHO cells expressing TRPV1 receptors (IC50 values are 0.6 and 0.8 nM for capsaicin (Cat. No. 0462) and acid-induced Ca2+ uptake, respectively). Exhibits >4000-fold selectivity for TRPV1 over other TRP channels. Blocks capsaicin-induced flinch response and causes hyperthermia in rats. Orally available and non-CNS penetrant. Purity 97%. MW (observed): 472.42 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-Amino-5-[[2-[(2-methoxyethyl)amino]-6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2(1H)-quinoxalinone |
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| Gene, Accession, CAS # | CAS: 939040-79-6 |
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| Catalog # | 4330/1 |
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| Price | |
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| Order / More Info | AMG 21629 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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