| 产品详情 |
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| Antigenic Specificity | Bif1 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 2.5 µg/mL, peptide-ELISA: 1:32000, Western Blot: 0.3-1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bif1 Polyclonal Antibody. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family such as Bax appear to control the activation of these enzymes. Bax activity was found to be regulated by its association with Bax-interacting factor 1 (BIF), a member of the endophilin B family that is associated with intracellular membranes. Following this interaction, Bax undergoes a conformational change and translocates to mitochondrial membranes. The Bax/BIF interaction appears to be enhanced by apoptotic stimuli, suggesting that BIF acts as the trigger to activate Bax, and as suppression of |
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| Immunogen | n/a |
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| Other Names | BIF1, Bif-1, CGI-61, KIAA0491, dJ612B15.2 |
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| Gene, Accession # | Entrez: 51100; Uniprot: Q9Y371 |
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| Catalog # | PA1-9017 |
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| Price | |
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| Order / More Info | Bif1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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