| 产品详情 |
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| Antigenic Specificity | CD46 |
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| Clone | M177 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1:50, Flow Cytometry: 1:50, Functional Assay: 1:50, Immunohistochemistry (Frozen): 1:50, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD46 Monoclonal Antibody (M177). CD46, also designated membrane cofactor protein, is a 45-70 kDa protein with genetic and tissue-specific heterogeneity. It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to down-regulate the activation of complement on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. The isoforms differ in the length. CD46 cDNA encodes a signal sequence fo |
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| Immunogen | n/a |
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| Other Names | AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10 |
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| Gene, Accession # | Entrez: 4179; Uniprot: P15529 |
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| Catalog # | MA1-40183 |
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| Price | |
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| Order / More Info | CD46 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26673143 |
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| 产品资料 |
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