| 产品详情 |
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| Antigenic Specificity | p600 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:500-1:2,000, Immunoprecipitation: 10 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p600 Polyclonal Antibody. E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation. |
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| Immunogen | n/a |
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| Other Names | 600 kDa retinoblastoma protein-associated factor, KIAA0462, KIAA1307, N-recognin-4, p600, RBAF600, retinoblastoma-associated factor 600-like protein, retinoblastoma-associated factor of 600 kDa, zinc finger UBR1-type protein 1, zinc finger, UBR1 type 1, ZUBR1 |
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| Gene, Accession # | Entrez: 23352; Uniprot: Q5T4S7 |
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| Catalog # | A302-277A-T |
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| Price | |
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| Order / More Info | p600 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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