| 产品详情 |
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| Antigenic Specificity | ARAP1 |
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| Clone | ARAP1-2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ARAP1 Monoclonal Antibody (ARAP1-2). ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading. |
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| Immunogen | n/a |
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| Other Names | CENTD2, KIAA0782 |
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| Gene, Accession # | Entrez: 116985; Uniprot: Q96P48 |
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| Catalog # | MA1-19728 |
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| Price | |
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| Order / More Info | ARAP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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